Sepacore Easy Purification Systems: better and faster separation


By: Brigitte Pichon

BUCHI introduces the new Sepacore Easy Purification Systems. These preparative chromatography start-up packages enable the purification required after a chemical synthesis or the extraction of a natural product. As a first step toward automation, they allow to precisely control the flow rate and the eluent composition of the mobile phase. Compared with the use of an open glass column, the Easy Purification Systems enable an improved separation with a decreased purification cost.

The “Easy Synthesis” system featuring a 250 mL/min, 10 bar (145 psi) pumping system offers an ideal configuration for the purification of synthesis mixtures on flash cartridges. Compared with the manual purification, the accurate control of the gradient elution provides an increased resolution and therefore a higher purity of the collected fractions.

The “Easy Extract” system is designed for large sample loading such as natural extracts. For such applications, the 50 bar (725 psi) gradient system is able to feed large glass columns for the purification of several hundred grams of natural extract. Together with a controlled separation process, such a system also allows to significantly reduce the solvent consumption when compared with the manual feeding of the solvents on an open glass column.

Both systems can later on easily be upgraded to a completely automated system including UV and/or ELS detection, fraction collection and flexible computer control.

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